Methods| This study was approved by the ethics committee at University College London,
and written informed consent was obtained from the participants. A 3-T fMRI scan was
performed on 2 pain-free individuals (1 woman) and 4 agematched control individuals.
Participants received 24 mechanical stimuli (465 mN, 0.2-mm tip, 1-second duration) to their
right hand dorsum. Functional MRI results from thermal stimuli are not reported owing to
motion artifacts. Participants rated the intensity of both subjective sensation (0= no sensation …