User profiles for "author:Y Machado"
Yoan MachadoUniversity of British Columbia Verified email at ubc.ca Cited by 709 |
Influence of protein fold stability on immunogenicity and its implications for vaccine design
Introduction: In modern vaccinology and immunotherapy, recombinant proteins more and
more replace whole organisms to induce protective or curative immune responses …
more replace whole organisms to induce protective or curative immune responses …
[HTML][HTML] Brainstem dysfunction in SARS-COV-2 infection can be a potential cause of respiratory distress
…, M Chinchilla, Y Machado, Y Machado - Neurology …, 2020 - journals.lww.com
Background: A terrible pandemic, Covid-19, has captivated scientists to investigate if SARS-
CoV-2 virus infects the central nervous system (CNS). A crucial question is if acute …
CoV-2 virus infects the central nervous system (CNS). A crucial question is if acute …
Properties of biodiesel oils formulated using different biomass sources and their blends
MCG Albuquerque, YL Machado, AEB Torres… - Renewable Energy, 2009 - Elsevier
Biodiesel is an alternative diesel fuel which can be obtained from the transesterification of
vegetable oils with simple alcohols. This process decreases the viscosity, density and flash …
vegetable oils with simple alcohols. This process decreases the viscosity, density and flash …
Recognizing a mother's voice in the persistent vegetative state
…, M Chinchilla, Y Machado, Y Machado - Clinical EEG and …, 2007 - journals.sagepub.com
We studied an 8-year-old boy after a near-drowning left him in a vegetative state (VS) for 4
years before the study. Findings fulfilled all clinical criteria for the diagnosis of VS. The …
years before the study. Findings fulfilled all clinical criteria for the diagnosis of VS. The …
[HTML][HTML] Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen
Y Machado, R Freier, S Scheiblhofer… - Journal of Allergy and …, 2016 - Elsevier
Background The search for intrinsic factors, which account for a protein's capability to act as
an allergen, is ongoing. Fold stability has been identified as a molecular feature that affects …
an allergen, is ongoing. Fold stability has been identified as a molecular feature that affects …
[PDF][PDF] Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome
The main viral protease (3CL pro) is indispensable for SARS-CoV-2 replication. We
delineate the human protein substrate landscape of 3CL pro by TAILS substrate-targeted N …
delineate the human protein substrate landscape of 3CL pro by TAILS substrate-targeted N …
[HTML][HTML] Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction
In healthy skin, epidermis and dermis are anchored together at the dermal-epidermal
junction (DEJ), a specialized basement membrane pivotal for skin integrity and function …
junction (DEJ), a specialized basement membrane pivotal for skin integrity and function …
The Declaration of Sydney on human death
…, M de la C Garcia, M Chinchilla, Y Machado… - Journal of Medical …, 2007 - jme.bmj.com
On 5 August 1968, publication of the Harvard Committee's report on the subject of
“irreversible coma” established a standard for diagnosing death on neurological grounds …
“irreversible coma” established a standard for diagnosing death on neurological grounds …
Ligand-based virtual screening and in silico design of new antimalarial compounds using nonstochastic and stochastic total and atom-type quadratic maps
…, PE Ávila, K Kirchgatter, Y Machado - Journal of chemical …, 2005 - ACS Publications
Malaria has been one of the most significant public health problems for centuries. It affects
many tropical and subtropical regions of the world. The increasing resistance of Plasmodium …
many tropical and subtropical regions of the world. The increasing resistance of Plasmodium …
[HTML][HTML] Cytotoxic and antileishmanial effects of the monoterpene β-ocimene
JMS Sousa, TAL Nunes, RRL Rodrigues, JPA Sousa… - Pharmaceuticals, 2023 - mdpi.com
Leishmaniasis is a group of infectious-parasitic diseases with high mortality rates, and
endemic in many regions of the globe. The currently available drugs present serious …
endemic in many regions of the globe. The currently available drugs present serious …