Mast cell disease or mastocytosis is a heterogeneous group of clinical disorders
characterized by the proliferation and accumulation of mast cells in a variety of tissues, most …

Abstract The Flexner Report of 1910 transformed the nature and process of medical
education in America with a resulting elimination of proprietary schools and the …

Type 1 Gaucher's disease (GD) is recognized for striking but unexplained phenotypic
diversity. Rarely, severe pulmonary hypertension (PH) may occur in GD but its clinical …

We offer a systematic strategy that situates clinical ethical reasoning within the paradigm of
clinical reasoning. The trajectory of this strategy parallels clinical reasoning: a plain …

Common variable immunodeficiency (CVID) is a primary immunodeficiency disease
characterized by low serum immunoglobulins IgG, IgA, and usually IgM. The central immune …

Acute fatty liver of pregnancy was diagnosed in nine patients over a 10-year period. Eight
patients had severe hepatic dysfunction typical for this syndrome and one had subclinical …

In a group of 52 patients receiving continuous intravenous heparin, 16 developed
thrombocytopenia (platelets< 100 000/mm3). Ten of the 16 patients who had …

THE association of intrauterine fetal death and maternal disseminated intravascular
coagulation is well established and generally referred to as the" fetal-death syndrome." 1 2 3 …

Sickle Myonecrosis Revisited Page 1 REVIEW Sickle Myonecrosis Revisited SRIDHAR MANI,
MD, THOMAS P. DUFFY, MD, NewHaven, Connecticut This review focuses on the classification …

Systemic mastocytosis (SM) is a rare disorder with important perioperative implications. The
physiological stress of operative procedures and a variety of anesthetic and analgesic …