Development of projection neuron types, axon pathways, and patterned connections of the mammalian cortex

DDM O'Leary, SE Koester - Neuron, 1993 - Elsevier
The mammalian neocortex processes visual, auditory, and somatic sensation, giving rise to
perception and initiatingvoluntarymotor responses. Thesefunctions are performed through …

[HTML][HTML] The genotype-tissue expression (GTEx) project

J Lonsdale, J Thomas, M Salvatore, R Phillips, E Lo… - Nature …, 2013 - nature.com
Genome-wide association studies have identified thousands of loci for common diseases,
but, for the majority of these, the mechanisms underlying disease susceptibility remain …

Functional classes of cortical projection neurons develop dendritic distinctions by class-specific sculpting of an early common pattern

SE Koester, DD O'Leary - Journal of Neuroscience, 1992 - Soc Neuroscience
We demonstrate in rat neocortex that the distinct laminar arrangements of the apical
dendrites of two classes of layer 5 projection neurons, callosal and corticotectal, do not arise …

Directed growth of early cortical axons is influenced by a chemoattractant released from an intermediate target

LJ Richards, SE Koester, R Tuttle… - Journal of …, 1997 - Soc Neuroscience
Projection neurons throughout the mature mammalian neocortex extend efferent axons
either through the ventrolaterally positioned internal capsule to subcortical targets or through …

Axons of early generated neurons in cingulate cortex pioneer the corpus callosum

SE Koester, DD O'leary - Journal of Neuroscience, 1994 - Soc Neuroscience
The internal capsule and corpus callosum are the two major efferent axonal pathways of the
mammalian neocortex. Previous studies have shown that the first cortical axons to grow …

Connectional distinction between callosal and subcortically projecting cortical neurons is determined prior to axon extension

SE Koester, DDM O'Leary - Developmental biology, 1993 - Elsevier
In adult rats, layer 5 cortical neurons send axons through the corpus callosum to
contralateral cortex or through the internal capsule to subcortical targets, but individual …

[HTML][HTML] Mouse maps of gene expression in the brain

SE Koester, TR Insel - Genome biology, 2007 - Springer
Mouse maps of gene expression in the brain | Genome Biology Skip to main content
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Development of projection neurons of the mammalian cerebral cortex

SE Koester, DDM O'Leary - Progress in brain research, 1994 - Elsevier
Publisher Summary This chapter summarizes the recent studies on the development of two
distinct classes of efferent projection neurons in the mammalian cortex: the callosal and …

[PDF][PDF] Transcriptional regulation of axon pathfinding

MM Daston, SE Koester - Neuron, 1996 - cell.com
Maryellen M. Daston* and Susan E. Koester† These transcription factors act at different
stages of* Molecular Neurobiology Laboratory neuron differentiation but not necessarily in …

Development of a consensus approach for return of pathology incidental findings in the Genotype-Tissue Expression (GTEx) project

NC Lockhart, CJ Weil, LJ Carithers, SE Koester… - Journal of medical …, 2018 - jme.bmj.com
The active debate about the return of incidental or secondary findings in research has
primarily focused on return to research participants, or in some cases, family members …