New insights into the molecular mechanisms of general anaesthetics
PL Chau - British journal of pharmacology, 2010 - Wiley Online Library
This paper provides new insights of how general anaesthetic research should be carried out
in the future by an analysis of what we know, what we do not know and what we would like …
in the future by an analysis of what we know, what we do not know and what we would like …
A new order parameter for tetrahedral configurations
PL Chau, AJ Hardwick - Molecular Physics, 1998 - Taylor & Francis
A new order parameter, S, is introduced to test for tetrahedral configurations. It is applied to
analyse the results of three simulations:(1) molecular dynamics simulation of ice Ih …
analyse the results of three simulations:(1) molecular dynamics simulation of ice Ih …
My body, your body, our bodies
J Herring, PL Chau - Medical Law Review, 2007 - academic.oup.com
Is your body yours? This may seem a strange question to ask, eliciting the immediate
response,'of course it is; who else's could it be?'1 Although there has been much debate …
response,'of course it is; who else's could it be?'1 Although there has been much debate …
[HTML][HTML] Prediction of 5-HT3 receptor agonist-binding residues using homology modeling
DC Reeves, MFR Sayed, PL Chau, KL Price… - Biophysical journal, 2003 - cell.com
HT 3 receptors demonstrate significant structural and functional homology to other members
of the Cys-loop ligand-gated ion channel superfamily. The extracellular domains of these …
of the Cys-loop ligand-gated ion channel superfamily. The extracellular domains of these …
The true amphipathic nature of graphene flakes: a versatile 2D stabilizer
AW Kuziel, KZ Milowska, PL Chau, S Boncel… - Advanced …, 2020 - Wiley Online Library
The fundamental colloidal properties of pristine graphene flakes remain incompletely
understood, with conflicting reports about their chemical character, hindering potential …
understood, with conflicting reports about their chemical character, hindering potential …
Defining, assigning and designing sex
PL Chau, J Herring - International Journal of Law, Policy and the …, 2002 - academic.oup.com
This article challenges the distinction the law draws between male and female. It focuses on
the legal and medical treatment of intersexual people. Analysing the nature and rate of …
the legal and medical treatment of intersexual people. Analysing the nature and rate of …
[HTML][HTML] Locating an antagonist in the 5-HT3 receptor binding site using modeling and radioligand binding
AJ Thompson, KL Price, DC Reeves, SL Chan… - Journal of biological …, 2005 - ASBMB
We have used a homology model of the extracellular domain of the 5-HT 3 receptor to dock
granisetron, a 5-HT 3 receptor antagonist, into the binding site using AUTODOCK. This …
granisetron, a 5-HT 3 receptor antagonist, into the binding site using AUTODOCK. This …
Computer simulation of the structural effect of pressure on the hydrophobic hydration of methane
PL Chau, RL Mancera - Molecular Physics, 1999 - Taylor & Francis
Monte Carlo simulations have been carried out on solutions containing one methane solute
in 499 water molecules, at pressures of 1, 100, 200, 400, 800 and 1600 atm and 320 K. We …
in 499 water molecules, at pressures of 1, 100, 200, 400, 800 and 1600 atm and 320 K. We …
Molecular recognition: 3D surface structure comparison by gnomonic projection
PL Chau, PM Dean - Journal of Molecular Graphics, 1987 - Elsevier
This paper outlines a method for gnomonic projection of a molecular surface and a novel
application of it to the problem of surface comparison. Semiregular arrays of points are …
application of it to the problem of surface comparison. Semiregular arrays of points are …
Exploring ligand recognition and ion flow in comparative models of the human GABA type A receptor
We present two comparative models of the GABAA receptor. Model 1 is based on the 4-Å
resolution structure of the nicotinic acetylcholine receptor from Torpedo marmorata and …
resolution structure of the nicotinic acetylcholine receptor from Torpedo marmorata and …