Transglutaminase inhibition reduces fibrosis and preserves function in experimental chronic kidney disease

TS Johnson, M Fisher, JL Haylor, Z Hau… - Journal of the …, 2007 - journals.lww.com
Progressive tissue fibrosis is involved in debilitating diseases that affect organs including the
lungs, liver, heart, skin, and kidneys. Recent evidence suggests that tissue …

Tissue transglutaminase and the progression of human renal scarring

TS Johnson, AF El-Koraie, NJ Skill… - Journal of the …, 2003 - journals.lww.com
Experimental renal scarring indicates that tissue transglutaminase (tTg) may be associated
with the accumulation of extracellular matrix (ECM), both indirectly via TGF-β1 activation and …

Transglutaminase transcription and antigen translocation in experimental renal scarring

TS Johnson, NJ Skill, AM El Nahas… - Journal of the …, 1999 - journals.lww.com
It was recently demonstrated that renal tissue transglutaminase (tTg) protein and its catalytic
product the ε (γ-glutamyl) lysine protein cross-link are significantly increased in the subtotal …

[HTML][HTML] Increases in renal ε-(γ-glutamyl)-lysine crosslinks result from compartment-specific changes in tissue transglutaminase in early experimental diabetic …

NJ Skill, M Griffin, AM El Nahas, T Sanai, JL Haylor… - Laboratory …, 2001 - Elsevier
Diabetic nephropathy (DN) is characterized by an early, progressive expansion and
sclerosis of the glomerular mesangium leading to glomerulosclerosis. This is associated …

Obligation for transparency regarding treating physician credentials at academic health centres

PJ Martin, NJ Skill, LG Koniaris - Journal of medical ethics, 2018 - jme.bmj.com
Academic health centres have historically treated patients with the most complex of
diseases, served as training grounds to teach the next generations of physicians and …

WD-OPW-425G. 1001 west 10th Street Indianapolis, IN 46202 Email: nskill@ iupui. ed u

NJ Skill - 2008 - journals.physiology.org
Portal hypertension (PHT) is a common complication of liver cirrhosis and significantly
increases morbidity and mortality. Abrogation of PHT using NSAIDs has demonstrated that …

Articles in PresS. Am J Physiol Gastrointest Liver Physiol (July 23, 2009). doi: 10.1152/ajpgi. 00229.2009

NG Theodorakis, YN Wang, JM Wu, MA Maluccio… - 2009 - journals.physiology.org
Portal hypertension (PHT) is a complication of liver cirrhosis and directly increases mortality
and morbidity by increasing the propensity of venous hemorrhage. There are two main …