User profiles for "author:Michelle McGowan"

Michelle McGowan

Mayo Clinic
Verified email at cchmc.org
Cited by 2158

[HTML][HTML] Big data, open science and the brain: lessons learned from genomics

S Choudhury, JR Fishman, ML McGowan… - Frontiers in human …, 2014 - frontiersin.org
The BRAIN Initiative aims to break new ground in the scale and speed of data collection in
neuroscience, requiring tools to handle data in the magnitude of yottabytes (1024). The …

Integrating genomics into clinical oncology: ethical and social challenges from proponents of personalized medicine

ML McGowan, RA Settersten Jr, ET Juengst… - … Oncology: Seminars and …, 2014 - Elsevier
Introduction The use of molecular tools to individualize health care, predict appropriate
therapies, and prevent adverse health outcomes has gained significant traction in the field of …

Serving epigenetics before its time

ET Juengst, JR Fishman, ML McGowan, RA Settersten - Trends in Genetics, 2014 - cell.com
Society prizes the rapid translation of basic biological science into ways to prevent human
illness. However, the premature rush to take murine epigenetic findings in these directions …

[HTML][HTML] Citizen science or scientific citizenship? Disentangling the uses of public engagement rhetoric in national research initiatives

JP Woolley, ML McGowan, HJA Teare, V Coathup… - BMC medical …, 2016 - Springer
Background The language of “participant-driven research,”“crowdsourcing” and “citizen
science” is increasingly being used to encourage the public to become involved in research …

From “personalized” to “precision” medicine: the ethical and social implications of rhetorical reform in genomic medicine

E Juengst, ML McGowan, JR Fishman… - Hastings Center …, 2016 - Wiley Online Library
Since the late 1980s, the human genetics and genomics research community has been
promising to usher in a “new paradigm for health care”—one that uses molecular profiling to …

[HTML][HTML] Looking back: egg donors' retrospective evaluations of their motivations, expectations, and experiences during their first donation cycle

NJ Kenney, ML McGowan - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To survey motivations, expectations, and experiences of egg donors in the
United States and their assessments of physical, psychological, and social after-effects of …

Personal genomics and individual identities: motivations and moral imperatives of early users

ML McGowan, JR Fishman… - New Genetics and …, 2010 - Taylor & Francis
Since 2007, consumer genomics companies have marketed personal genome scanning
services to assess users' genetic predispositions to a variety of complex diseases and traits …

[PDF][PDF] Harmonizing clinical sequencing and interpretation for the eMERGE III network

H Zouk, E Venner, NJ Lennon, DM Muzny… - The American Journal of …, 2019 - cell.com
The advancement of precision medicine requires new methods to coordinate and deliver
genetic data from heterogeneous sources to physicians and patients. The eMERGE III …

After the revolution? Ethical and social challenges in 'personalized genomic medicine'

ET Juengst, RA Settersten, JR Fishman… - Personalized …, 2012 - Future Medicine
Personalized genomic medicine (PGM) is a goal that currently unites a wide array of
biomedical initiatives, and is promoted as a 'new paradigm for healthcare'by its champions …

Adolescent and parental attitudes about return of genomic research results: focus group findings regarding decisional preferences

ML McGowan, CA Prows… - Journal of Empirical …, 2018 - journals.sagepub.com
Opportunities to participate in genomic sequencing studies, as well as recommendations to
screen for variants in 59 medically actionable genes anytime clinical genomic sequencing is …