What causes the onset of psychosis?
It has become increasingly clear that the simple neurodevelopmental model fails to explain
many aspects of schizophrenia including the timing of the onset, and the nature of the …
many aspects of schizophrenia including the timing of the onset, and the nature of the …
A systematic review of the parenting and outcomes experienced by offspring of mothers with borderline personality pathology: Potential mechanisms and clinical …
There is growing interest in whether the parenting strategies and offspring outcomes of
mothers with borderline personality disorder (BPD) differ from those of mothers without BPD …
mothers with borderline personality disorder (BPD) differ from those of mothers without BPD …
[HTML][HTML] Subjective experience and meaning of delusions in psychosis: a systematic review and qualitative evidence synthesis
R Ritunnano, J Kleinman, DW Oshodi… - The Lancet …, 2022 - thelancet.com
Background Delusions are a common transdiagnostic feature of psychotic disorders, and
their treatment remains suboptimal. Despite the pressing need to better understand the …
their treatment remains suboptimal. Despite the pressing need to better understand the …
Regionally localized thinning of the cerebral cortex in schizophrenia
GR Kuperberg, MR Broome, PK McGuire… - Archives of general …, 2003 - jamanetwork.com
Background Schizophrenia is characterized by small reductions in cortical gray matter
volume, particularly in the temporal and prefrontal cortices. The question of whether cortical …
volume, particularly in the temporal and prefrontal cortices. The question of whether cortical …
Delusion formation and reasoning biases in those at clinical high risk for psychosis
BackgroundCognitive models propose that faulty appraisal of anomalous experiences is
critical in developing psychosis, particularly delusions. A data gathering bias may be …
critical in developing psychosis, particularly delusions. A data gathering bias may be …
Alterations in white matter evident before the onset of psychosis
F Carletti, JB Woolley, S Bhattacharyya… - Schizophrenia …, 2012 - academic.oup.com
Background Psychotic disorders are associated with widespread reductions in white matter
(WM) integrity. However, the stage at which these abnormalities first appear and whether …
(WM) integrity. However, the stage at which these abnormalities first appear and whether …
Superior temporal lobe dysfunction and frontotemporal dysconnectivity in subjects at risk of psychosis and in first‐episode psychosis
Background: Superior temporal lobe dysfunction is a robust finding in functional
neuroimaging studies of schizophrenia and is thought to be related to a disruption of fronto …
neuroimaging studies of schizophrenia and is thought to be related to a disruption of fronto …
Outreach and support in south London (OASIS): implementation of a clinical service for prodromal psychosis and the at risk mental state
BackgroundWhile recent research points to the potential benefits of clinical intervention
before the first episode of psychosis, the logistical feasibility of this is unclear. AimsTo …
before the first episode of psychosis, the logistical feasibility of this is unclear. AimsTo …
Brain-wide analysis of functional connectivity in first-episode and chronic stages of schizophrenia
Published reports of functional abnormalities in schizophrenia remain divergent due to lack
of staging point-of-view and whole-brain analysis. To identify key functional-connectivity …
of staging point-of-view and whole-brain analysis. To identify key functional-connectivity …
Misattribution of external speech in patients with hallucinations and delusions
Background: One of the main cognitive models of positive symptoms in schizophrenia
proposes that they arise through impaired self-monitoring. This is supported by evidence of …
proposes that they arise through impaired self-monitoring. This is supported by evidence of …