Cardiovascular risk in post-myocardial infarction patients: nationwide real world data demonstrate the importance of a long-term perspective
T Jernberg, P Hasvold, M Henriksson… - European heart …, 2015 - academic.oup.com
Aims Long-term disease progression following myocardial infarction (MI) is not well
understood. We examined the risk of subsequent cardiovascular events in patients …
understood. We examined the risk of subsequent cardiovascular events in patients …
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
Cancers have dysfunctional redox regulation resulting in reactive oxygen species
production, damaging both DNA and free dNTPs. The MTH1 protein sanitizes oxidized …
production, damaging both DNA and free dNTPs. The MTH1 protein sanitizes oxidized …
[HTML][HTML] Swedish experience-based value sets for EQ-5D health states
K Burström, S Sun, UG Gerdtham, M Henriksson… - Quality of Life …, 2014 - Springer
Abstract Purpose To estimate Swedish experience-based value sets for EQ-5D health states
using general population health survey data. Methods Approximately 45,000 individuals …
using general population health survey data. Methods Approximately 45,000 individuals …
Randomized clinical trial of the costs of open and laparoscopic surgery for colonic cancer
M Janson, I Björholt, P Carlsson… - Journal of British …, 2004 - academic.oup.com
Background There has been no randomized clinical trial of the costs of laparoscopic colonic
resection (LCR) compared with those of open colonic resection (OCR) in the treatment of …
resection (LCR) compared with those of open colonic resection (OCR) in the treatment of …
Cost-effectiveness of treating acute coronary syndrome patients with ticagrelor for 12 months: results from the PLATO study
E Nikolic, M Janzon, O Hauch, L Wallentin… - European heart …, 2013 - academic.oup.com
Aims The efficacy and safety of ticagrelor vs. clopidogrel in patients with acute coronary
syndromes (ACS) are well documented in the PLATelet inhibition and patient Outcomes trial …
syndromes (ACS) are well documented in the PLATelet inhibition and patient Outcomes trial …
A systematic review of cost-effectiveness models in type 1 diabetes mellitus
M Henriksson, R Jindal, C Sternhufvud… - …, 2016 - Springer
Background Critiques of cost-effectiveness modelling in type 1 diabetes mellitus (T1DM) are
scarce and are often undertaken in combination with type 2 diabetes mellitus (T2DM) …
scarce and are often undertaken in combination with type 2 diabetes mellitus (T2DM) …
[HTML][HTML] Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
N Bonagas, NMS Gustafsson, M Henriksson, P Marttila… - Nature cancer, 2022 - nature.com
The folate metabolism enzyme MTHFD2 (methylenetetrahydrofolate dehydrogenase/
cyclohydrolase) is consistently overexpressed in cancer but its roles are not fully …
cyclohydrolase) is consistently overexpressed in cancer but its roles are not fully …
[HTML][HTML] Disease progression modeling for economic evaluation in nonalcoholic fatty liver disease—a systematic review
L Gruneau, M Ekstedt, S Kechagias… - Clinical Gastroenterology …, 2023 - Elsevier
Abstract Background & Aims Globally, 25% of people have Non-Alcoholic Fatty Liver
Disease (NAFLD) and currently there are no approved pharmacological treatments for …
Disease (NAFLD) and currently there are no approved pharmacological treatments for …
[HTML][HTML] Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells
Cancer cells fuel their increased need for nucleotide supply by upregulating one-carbon
(1C) metabolism, including the enzymes methylenetetrahydrofolate dehydrogenase …
(1C) metabolism, including the enzymes methylenetetrahydrofolate dehydrogenase …
[HTML][HTML] Experience-based Swedish TTO and VAS value sets for EQ-5D-5L health states
Abstract Background and Objective Although value sets for the five-level version of the
generic health-related quality-of-life instrument EQ-5D are emerging, there is still no value …
generic health-related quality-of-life instrument EQ-5D are emerging, there is still no value …