Autosomal-dominant polycystic kidney disease (ADPKD) is a common, progressive, adult-
onset disease that is an important cause of end-stage renal disease (ESRD), which requires …

Background Increased numbers of children with chronic illnesses and/or disabilities who
have complex care needs are living at home. Along with the transfer of care to the home …

Introduction Up to 35% of patients with a first episode of Clostridioides difficile infection (CDI)
develop recurrent CDI (rCDI), and of those, up to 65% experience multiple recurrences. A …

Preventable medical errors occur with alarming frequency in US hospitals. Questions to
address include what is a medical error, what errors occur most often, and what solutions …

Background Nurses working night shifts are at risk for sleep deprivation, which threatens
patient and nurse safety. Little nursing research has addressed napping, an effective …

Deep learning techniques are being rapidly applied to medical imaging tasks—from organ
and lesion segmentation to tissue and tumor classification. These techniques are becoming …

Results Patients treated with tolvaptan had lower eGFR slopes from baseline (mean±SD,−
2.20±2.18 ml/min per 1.73 m 2 per year) and from month 1 (mean±SD,− 1.97±2.44 ml/min …

Background The formation and growth of cysts in kidneys, and often liver, in autosomal
dominant polycystic kidney disease (ADPKD) cause progressive increases in total kidney …

While we have some understanding of the impact caring for children with complex care
needs has on families, little is known about how these families experience participation. This …

Introduction Maintaining fluid intake sufficient to reduce arginine vasopressin (AVP)
secretion has been hypothesised to slow kidney cyst growth in autosomal dominant …