User profiles for "author:Lauren Rayner"

Lauren Rayner

King's College London, Institute of Psychiatry
Verified email at kcl.ac.uk
Cited by 3838

The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis

F Matcham, L Rayner, S Steer, M Hotopf - Rheumatology, 2013 - academic.oup.com
Objective. There is substantial uncertainty regarding the prevalence of depression in RA. We
conducted a systematic review aiming to describe the prevalence of depression in RA …

[HTML][HTML] The impact of rheumatoid arthritis on quality-of-life assessed using the SF-36: a systematic review and meta-analysis

F Matcham, IC Scott, L Rayner, M Hotopf… - Seminars in arthritis and …, 2014 - Elsevier
Objective The assessment of health-related quality-of-life (HRQoL) in rheumatoid arthritis
(RA) is becoming increasingly common in both research and clinical practice. One of the …

Antidepressants for depression in physically ill people

L Rayner, A Price, A Evans, K Valsraj… - Cochrane Database …, 2010 - cochranelibrary.com
Background There is an increased risk of depression in people with a physical illness.
Depression is associated with reduced treatment adherence, poor prognosis, increased …

[HTML][HTML] Depression in patients with chronic pain attending a specialised pain treatment centre: prevalence and impact on health care costs

L Rayner, M Hotopf, H Petkova, F Matcham, A Simpson… - Pain, 2016 - journals.lww.com
1. Background Chronic pain and depression are each prevalent and often co-occur. 5
Although the underlying mechanism of the interaction between pain and depression is not …

Antidepressants for the treatment of depression in palliative care: systematic review and meta-analysis

L Rayner, A Price, A Evans, K Valsraj… - Palliative …, 2011 - journals.sagepub.com
Depression can exacerbate symptoms associated with life-threatening illness and increase
disability and distress. In palliative care, depression occurs in a context of multiple …

The development of evidence-based European guidelines on the management of depression in palliative cancer care

L Rayner, A Price, M Hotopf, IJ Higginson - European journal of cancer, 2011 - Elsevier
Depression is common in cancer patients, particularly those with advanced disease. It is
associated with adverse outcomes such as increased pain, disability and poorer prognosis …

The factor structure of the PHQ-9 in palliative care

J Chilcot, L Rayner, W Lee, A Price, L Goodwin… - Journal of …, 2013 - Elsevier
OBJECTIVES: The Primary Care Evaluation of Mental Disorders Patient Health
Questionnaire (PRIME-MD PHQ-9) is a common screening tool designed to facilitate …

Antidepressants for the treatment of depression in neurological disorders: a systematic review and meta-analysis of randomised controlled trials

A Price, L Rayner, E Okon-Rocha, A Evans… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background Despite the high prevalence of depression in people with neurological
disorders, no previous study has sought to summarise existing evidence on the use of …

Associations between depression, arterial stiffness, and metabolic syndrome among adults in the UK Biobank population study: a mediation analysis

A Dregan, L Rayner, KAS Davis, I Bakolis… - JAMA …, 2020 - jamanetwork.com
Importance Previous research has linked a history of depression with arterial stiffness (AS)
during midlife. Objective To assess the association of depression with elevated midlife AS …

The clinical epidemiology of depression in palliative care and the predictive value of somatic symptoms: cross-sectional survey with four-week follow-up

L Rayner, W Lee, A Price, B Monroe… - Palliative …, 2011 - journals.sagepub.com
This cross-sectional survey aimed to determine the prevalence and remission of depression
in patients receiving palliative care and to ascertain the predictive value of somatic …