Optimization of chemically defined cell culture media–replacing fetal bovine serum in mammalian in vitro methods

J Van der Valk, D Brunner, K De Smet… - Toxicology in vitro, 2010 - Elsevier
Quality assurance is becoming increasingly important. Good laboratory practice (GLP) and
good manufacturing practice (GMP) are now established standards. The biomedical field …

Human internal and external exposure to PBDEs–a review of levels and sources

M Frederiksen, K Vorkamp, M Thomsen… - International journal of …, 2009 - Elsevier
This paper reviews the existing literature on human exposure to polybrominated diphenyl
ethers (PBDEs), with particular focus on external exposure routes (eg dust, diet, and air) and …

The comet assay as a rapid test in biomonitoring occupational exposure to DNA-damaging agents and effect of confounding factors

P Møller, LE Knudsen, S Loft, H Wallin - Cancer epidemiology biomarkers & …, 2000 - AACR
Within the last decade, the comet assay has been used with increasing popularity to
investigate the level of DNA damage in terms of strand breaks and alkaline labile sites in …

Chromosomal aberrations in lymphocytes predict human cancer: a report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH)

L Hagmar, S Bonassi, U Strömberg, A Brøgger… - Cancer research, 1998 - AACR
Chromosomal aberrations (CAs), sister chromatid exchanges (SCEs), and micronuclei (MN)
in peripheral blood lymphocytes have for decades been used as cytogenetic biomarkers to …

Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens

S Bonassi, L Hagmar, U Strömberg, AH Montagud… - Cancer Research, 2000 - AACR
An increased risk of cancer in healthy individuals with high levels of chromosomal
aberrations (CAs) in peripheral blood lymphocytes has been described in recent …

Chromosomal aberrations and SCEs as biomarkers of cancer risk

H Norppa, S Bonassi, IL Hansteen, L Hagmar… - Mutation Research …, 2006 - Elsevier
Previous studies have suggested that the frequency of chromosomal aberrations (CAs), but
not of sister chromatid exchanges (SCEs), predicts cancer risk. We have further examined …

Chromosomal aberration frequency in lymphocytes predicts the risk of cancer: results from a pooled cohort study of 22 358 subjects in 11 countries

S Bonassi, H Norppa, M Ceppi, U Strömberg… - …, 2008 - academic.oup.com
Mechanistic evidence linking chromosomal aberration (CA) to early stages of cancer has
been recently supported by the results of epidemiological studies that associated CA …

Oxidative stress associated with exercise, psychological stress and life-style factors

P Møller, H Wallin, LE Knudsen - Chemico-biological interactions, 1996 - Elsevier
Oxidative stress is a cellular or physiological condition of elevated concentrations of reactive
oxygen species that cause molecular damage to vital structures and functions. Several …

Personal exposure to ultrafine particles and oxidative DNA damage

PS Vinzents, P Møller, M Sørensen… - Environmental …, 2005 - ehp.niehs.nih.gov
Exposure to ultrafine particles (UFPs) from vehicle exhaust has been related to risk of
cardiovascular and pulmonary disease and cancer, even though exposure assessment is …

Urinary excretion of phthalate metabolites, phenols and parabens in rural and urban Danish mother–child pairs

H Frederiksen, JKS Nielsen, TA Mørck… - International journal of …, 2013 - Elsevier
Some phthalates, parabens and phenols have shown adverse endocrine disrupting effects
in animal studies and are also suspected to be involved in human reproductive problems …