The mechanisms of Hedgehog signalling and its roles in development and disease
J Briscoe, PP Thérond - Nature reviews Molecular cell biology, 2013 - nature.com
The cloning of the founding member of the Hedgehog (HH) family of secreted proteins two
decades ago inaugurated a field that has diversified to encompass embryonic development …
decades ago inaugurated a field that has diversified to encompass embryonic development …
Specification of neuronal fates in the ventral neural tube
The generation of distinct classes of neurons at defined positions is a fundamental step in
the development of the vertebrate central nervous system. Recent work has begun to reveal …
the development of the vertebrate central nervous system. Recent work has begun to reveal …
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network
E Dessaud, AP McMahon, J Briscoe - 2008 - journals.biologists.com
Neuronal subtype specification in the vertebrate neural tube is one of the best-studied
examples of embryonic pattern formation. Distinct neuronal subtypes are generated in a …
examples of embryonic pattern formation. Distinct neuronal subtypes are generated in a …
[HTML][HTML] Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
…, A Kawakami, V Van Heyningen, TM Jessell, J Briscoe - Cell, 1997 - cell.com
Distinct classes of motor neurons and ventral interneurons are generated by the graded
signaling activity of Sonic hedgehog (Shh). Shh controls neuronal fate by establishing …
signaling activity of Sonic hedgehog (Shh). Shh controls neuronal fate by establishing …
Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
During vertebrate development, the specification of distinct cell types is thought to be
controlled by inductive signals acting at different concentration thresholds. The degree of …
controlled by inductive signals acting at different concentration thresholds. The degree of …
[HTML][HTML] A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
Distinct classes of neurons are generated at defined positions in the ventral neural tube in
response to a gradient of Sonic Hedgehog (Shh) activity. A set of homeodomain …
response to a gradient of Sonic Hedgehog (Shh) activity. A set of homeodomain …
Protean and boundaryless careers: An empirical exploration
JP Briscoe, DT Hall, RLF DeMuth - Journal of vocational behavior, 2006 - Elsevier
While the constructs of protean and boundaryless careers have informed career theory for
years, rigorous empirical examinations of these career models have lagged behind. This …
years, rigorous empirical examinations of these career models have lagged behind. This …
The interplay of boundaryless and protean careers: Combinations and implications
JP Briscoe, DT Hall - Journal of vocational behavior, 2006 - Elsevier
The boundaryless and protean career concepts are compared in this article. It is suggested
that the theories can be more finely delineated to produce more effective theory and …
that the theories can be more finely delineated to produce more effective theory and …
The protein tyrosine kinase JAK1 complements defects in interferon-α/β and-γ signal transduction
We have produced a cell line which lacks the protein tyrosine kinase JAK1 and is completely
defective in interferon response. Complementation of this mutant with JAK1 restored the …
defective in interferon response. Complementation of this mutant with JAK1 restored the …
Employability during unemployment: Adaptability, career identity and human and social capital
Recently, Fugate et al.[Fugate, M., Kinicki, AJ, & Ashforth, BE (2004). Employability: A
psycho-social construct, its dimensions, and applications. Journal of Vocational Behavior, 65 …
psycho-social construct, its dimensions, and applications. Journal of Vocational Behavior, 65 …