[PDF][PDF] Inferring genetic ancestry: opportunities, challenges, and implications

CD Royal, J Novembre, SM Fullerton… - The American Journal of …, 2010 - cell.com
Increasing public interest in direct-to-consumer (DTC) genetic ancestry testing has been
accompanied by growing concern about issues ranging from the personal and societal …

Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease

E Peprah, H Xu, F Tekola-Ayele, CD Royal - Public Health Genomics, 2015 - karger.com
Genomic research is one of the tools for elucidating the pathogenesis of diseases of global
health relevance and paving the research dimension to clinical and public health translation …

The impact of environmental factors on monogenic Mendelian diseases

AM Tukker, CD Royal, AB Bowman… - Toxicological …, 2021 - academic.oup.com
Environmental factors and gene-environment interactions modify the variable expressivity,
progression, severity, and onset of some classic (monogenic) Mendelian-inherited genetic …

[HTML][HTML] Will precision medicine move us beyond race?

VL Bonham, SL Callier, CD Royal - The New England journal of …, 2016 - ncbi.nlm.nih.gov
Health care providers have long struggled with the utility of race in the prescribing and
dosing of medications. It is widely accepted that self-identified race often correlates with …

Anthropologists' views on race, ancestry, and genetics

JK Wagner, JH Yu, JO Ifekwunigwe… - American Journal of …, 2017 - Wiley Online Library
Controversies over race conceptualizations have been ongoing for centuries and have been
shaped, in part, by anthropologists. Objective To assess anthropologists' views on race …

A qualitative analysis of how anthropologists interpret the race construct

JO Ifekwunigwe, JK Wagner, JH Yu… - American …, 2017 - Wiley Online Library
This article assesses anthropological thinking about the race concept and its applications.
Drawn from a broader national survey of geneticists' and anthropologists' views on race, in …

[HTML][HTML] Tilting at windmills no longer: a data-driven discussion of DTC DNA ancestry tests

JK Wagner, JD Cooper, R Sterling, CD Royal - Genetics in Medicine, 2012 - nature.com
Purpose: Discussions about direct-to-consumer (DTC) DNA ancestry tests have to date been
based primarily on conjectures, speculation, and anecdotes, despite the industry being more …

[HTML][HTML] Regional differences in awareness and attitudes regarding genetic testing for disease risk and ancestry

CR Jonassaint, ER Santos, CM Glover, PW Payne… - Human genetics, 2010 - Springer
Little is known about the lay public's awareness and attitudes concerning genetic testing and
what factors influence their perspectives. The existing literature focuses mainly on ethnic …

A content analysis of the views of genetics professionals on race, ancestry, and genetics

SC Nelson, JH Yu, JK Wagner, TM Harrell… - AJOB empirical …, 2018 - Taylor & Francis
Over the past decade, the proliferation of genetic studies on human health and disease has
reinvigorated debates about the appropriate role of race and ancestry in research and …

Living with sickle cell disease: traversing 'race'and identity

CD Royal, CR Jonassaint… - … and Global Public …, 2014 - api.taylorfrancis.com
Objectives. Sickle cell disease (SCD) has a distinctive social history that continues to
influence research and clinical practice related to the disease. Despite the historical link …