User profiles for "author:Carl Montague"
Carl MontagueShook Services Verified email at ukzn.ac.za Cited by 9570 |
The perils of portliness: causes and consequences of visceral adiposity.
CT Montague, S O'Rahilly - Diabetes, 2000 - Am Diabetes Assoc
Although an individual's total fat mass predicts morbidities such as coronary artery disease
and diabetes, the anatomical distribution of adipose tissue is a strong and independent …
and diabetes, the anatomical distribution of adipose tissue is a strong and independent …
[HTML][HTML] Congenital leptin deficiency is associated with severe early-onset obesity in humans
CT Montague, IS Farooqi, JP Whitehead, MA Soos… - Nature, 1997 - nature.com
The extreme obesity of the obese (ob/ob) mouse is attributable to mutations in the gene
encoding leptin, an adipocyte-specific secreted protein which has profound effects on …
encoding leptin, an adipocyte-specific secreted protein which has profound effects on …
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene
RS Jackson, JWM Creemers, S Ohagi… - Nature …, 1997 - nature.com
Human obesity has an inherited component, but in contrast to rodent obesity, precise
genetic defects have yet to be defined1. A mutation of carboxypeptidase E (CPE), an …
genetic defects have yet to be defined1. A mutation of carboxypeptidase E (CPE), an …
Depot-and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution
CT Montague, JB Prins, L Sanders, JE Digby… - Diabetes, 1997 - Am Diabetes Assoc
Obese subjects with excess intra-abdominal fat deposition suffer greater adverse metabolic
consequences than do similarly overweight subjects with a predominantly subcutaneous …
consequences than do similarly overweight subjects with a predominantly subcutaneous …
Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.
M Adams, CT Montague, JB Prins… - The Journal of …, 1997 - Am Soc Clin Investig
Activation of peroxisome proliferator-activated receptor (PPAR) gamma, a nuclear receptor
highly expressed in adipocytes, induces the differentiation of murine preadipocyte cell lines …
highly expressed in adipocytes, induces the differentiation of murine preadipocyte cell lines …
Depot-related gene expression in human subcutaneous and omental adipocytes.
CT Montague, JB Prins, L Sanders, J Zhang… - Diabetes, 1998 - Am Diabetes Assoc
Human omental adipocytes display a range of biochemical properties that distinguish them
from adipocytes of subcutaneous origin. However, information about site-related gene …
from adipocytes of subcutaneous origin. However, information about site-related gene …
Characterization of the human, mouse and rat PGC1beta (peroxisome-proliferator-activated receptor-gamma co-activator 1beta) gene in vitro and in vivo
A Meirhaeghe, V Crowley, C Lenaghan… - Biochemical …, 2003 - portlandpress.com
PGC1α is a co-activator involved in adaptive thermogenesis, fatty-acid oxidation and
gluconeogenesis. We describe the identification of several isoforms of a new human PGC1α …
gluconeogenesis. We describe the identification of several isoforms of a new human PGC1α …
Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes
JE Digby, CT Montague, CP Sewter, L Sanders… - Diabetes, 1998 - Am Diabetes Assoc
Thiazolidinediones (TZDs) are a novel class of insulinsensitizing agents used in the
treatment of NIDDM and are potent agonists for the nuclear hormone receptor peroxisome …
treatment of NIDDM and are potent agonists for the nuclear hormone receptor peroxisome …
Barriers and facilitators to the uptake of voluntary medical male circumcision (VMMC) among adolescent boys in KwaZulu–Natal, South Africa
Epidemiological modelling has concluded that if voluntary medical male circumcision
(VMMC) is scaled up in high HIV prevalence settings it would lead to a significant reduction …
(VMMC) is scaled up in high HIV prevalence settings it would lead to a significant reduction …
[HTML][HTML] Implementation of adolescent-friendly voluntary medical male circumcision using a school based recruitment program in rural KwaZulu-Natal, South Africa
C Montague, N Ngcobo, G Mahlase, J Frohlich… - PloS one, 2014 - journals.plos.org
Background Epidemiological data from South Africa demonstrate that risk of human
immunodeficiency virus (HIV) infection in males increases dramatically after adolescence …
immunodeficiency virus (HIV) infection in males increases dramatically after adolescence …