Circadian Organization of Behavior and Physiology in Drosophila
Circadian clocks organize behavior and physiology to adapt to daily environmental cycles.
Genetic approaches in the fruit fly, Drosophila melanogaster, have revealed widely …
Genetic approaches in the fruit fly, Drosophila melanogaster, have revealed widely …
[HTML][HTML] Practical guidelines for managing adults with 22q11. 2 deletion syndrome
Abstract 22q11. 2 Deletion syndrome (22q11. 2DS) is the most common microdeletion
syndrome in humans, estimated to affect up to 1 in 2,000 live births. Major features of this …
syndrome in humans, estimated to affect up to 1 in 2,000 live births. Major features of this …
Autism spectrum disorders and epigenetics
D Grafodatskaya, B Chung, P Szatmari… - Journal of the American …, 2010 - Elsevier
OBJECTIVE: Current research suggests that the causes of autism spectrum disorders (ASD)
are multifactorial and include both genetic and environmental factors. Several lines of …
are multifactorial and include both genetic and environmental factors. Several lines of …
Functional impact of global rare copy number variation in autism spectrum disorders
The autism spectrum disorders (ASDs) are a group of conditions characterized by
impairments in reciprocal social interaction and communication, and the presence of …
impairments in reciprocal social interaction and communication, and the presence of …
[PDF][PDF] Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism
We present the largest exome sequencing study of autism spectrum disorder (ASD) to date
(n= 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to …
(n= 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to …
Rare coding variation provides insight into the genetic architecture and phenotypic context of autism
Some individuals with autism spectrum disorder (ASD) carry functional mutations rarely
observed in the general population. We explored the genes disrupted by these variants from …
observed in the general population. We explored the genes disrupted by these variants from …
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression
SA Selamat, BS Chung, L Girard, W Zhang… - Genome …, 2012 - genome.cshlp.org
Lung cancer is the leading cause of cancer death worldwide, and adenocarcinoma is its
most common histological subtype. Clinical and molecular evidence indicates that lung …
most common histological subtype. Clinical and molecular evidence indicates that lung …
Phenotypic spectrum associated with de novo and inherited deletions and duplications at 16p11. 2 in individuals ascertained for diagnosis of autism spectrum …
BA Fernandez, W Roberts, B Chung… - Journal of medical …, 2010 - jmg.bmj.com
Background Recurrent microdeletions and microduplications of∼ 555 kb at 16p11. 2 confer
susceptibility to autism spectrum disorder (ASD) in up to 1% of ASD patients. No physical or …
susceptibility to autism spectrum disorder (ASD) in up to 1% of ASD patients. No physical or …
Association of MTOR mutations with developmental brain disorders, including megalencephaly, focal cortical dysplasia, and pigmentary mosaicism
GM Mirzaa, CD Campbell, N Solovieff, CP Goold… - JAMA …, 2016 - jamanetwork.com
Importance Focal cortical dysplasia (FCD), hemimegalencephaly, and megalencephaly
constitute a spectrum of malformations of cortical development with shared neuropathologic …
constitute a spectrum of malformations of cortical development with shared neuropathologic …
Pediatric stroke among hong kong chinese subjects
B Chung, V Wong - Pediatrics, 2004 - publications.aap.org
Background. The incidence of pediatric stroke was estimated to be 2.5 to 2.7 cases per 100
000 children per year in North America and 13 cases per 100 000 children per year in …
000 children per year in North America and 13 cases per 100 000 children per year in …