Studies suggest that 1–3% of the general population in the United States unknowingly carry
a genetic risk factor for a common hereditary disease. Population genetic screening is the …

Ultraviolet radiation exposure is the leading cause of skin cancer, and childhood and
adolescence is a particularly susceptible life period for exposure. This systematic review …

Purpose We evaluated the impact of personal melanoma genomic risk information on sun-
related behaviors and psychological outcomes. Methods In this parallel group, open …

Precision public health is a relatively new field that integrates components of precision
medicine, such as human genomics research, with public health concepts to help improve …

Importance Patient-led surveillance is a promising new model of follow-up care following
excision of localized melanoma. Objective To determine whether patient-led surveillance in …

Background: Communication of personalized melanoma genomic risk information may
improve melanoma prevention behaviors. Methods: We evaluated the feasibility and …

Background There is mounting evidence of the benefit of risk‐stratified (risk‐tailored) cancer
population screening, when compared to standard approaches. However, shifting towards …

Background Previous studies suggest that polygenic risk scores (PRSs) may improve
melanoma risk stratification. However, there has been limited independent validation of PRS …

Polygenic risk scores (PRS) are becoming increasingly available in clinical practice to
evaluate cancer risk. However, little is known about health professionals' knowledge …

Data sharing is essential for promoting scientific discoveries and informed decision-making
in clinical practice. In 2013, PhRMA/EFPIA recognised the importance of data sharing and …