Genome-wide association studies have identified thousands of loci for common diseases,
but, for the majority of these, the mechanisms underlying disease susceptibility remain …

The Human Microbiome Project (HMP), funded as an initiative of the NIH Roadmap for
Biomedical Research (http://nihroadmap. nih. gov), is a multi-component community …

While conventional nutrition research has yielded biomarkers such as doubly labeled water
for energy metabolism and 24-h urinary nitrogen for protein intake, a critical need exists for …

Long-lived postmitotic cells, such as most human neurons, must respond effectively to
ongoing changes in neuronal stimulation or microenvironmental cues through …

ADX–adrenalectomized; BBB–blood-brain barrier; CNS–central nervous system; CORT–
corticosterone; bFGF–basic fibroblast growth factor; EAE–experimental autoimmune …

Institute of Child Health and Human Development, the National Institute of Mental Health,
and the National Institute of Neurological Disorders and Stroke (NINDS), was created to …

Abstract The National Institutes of Health (NIH) NeuroBioBank is a federally funded research
resource for human neurologic diseases and disorders. This chapter will discuss the …

Gene expression profiles in several brain regions of adult male rats were evaluated
following a d-amphetamine (AMPH) exposure paradigm previously established to produce …

Normal human tissues, bodily fluids, and other biospecimens of known quality are essential
for research to understand the development of cancer and other diseases and to develop …

The active debate about the return of incidental or secondary findings in research has
primarily focused on return to research participants, or in some cases, family members …