User profiles for "author:A J Newson"

Ainsley J. Newson

Professor of Bioethics, University of Sydney
Verified email at sydney.edu.au
Cited by 3483

The emergence and global spread of noninvasive prenatal testing

V Ravitsky, MC Roy, H Haidar… - Annual review of …, 2021 - annualreviews.org
Since its introduction in 2011, noninvasive prenatal testing (NIPT) has spread rapidly around
the world. It carries numerous benefits but also raises challenges, often related to …

[HTML][HTML] Cascade testing in familial hypercholesterolaemia: how should family members be contacted?

AJ Newson, SE Humphries - European Journal of Human Genetics, 2005 - nature.com
Cascade testing or screening provides an important mechanism for identifying people at risk
of a genetic condition. For some autosomal dominant conditions, such as familial …

Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice

EV Howman, KJ Fowler, AJ Newson… - Proceedings of the …, 2000 - National Acad Sciences
Centromere protein A (Cenpa for mouse, CENP-A for other species) is a histone H3-like
protein that is thought to be involved in the nucleosomal packaging of centromeric DNA …

Ethical aspects arising from non-invasive fetal diagnosis

AJ Newson - Seminars in Fetal and Neonatal Medicine, 2008 - Elsevier
Non-invasive prenatal diagnosis (NIPD) could significantly change the framework for testing
and screening in pregnancy. This chapter reviews the ethical implications of this technology …

Gene selection for the Australian reproductive genetic carrier screening project (“Mackenzie's Mission”)

EP Kirk, R Ong, K Boggs, T Hardy, S Righetti… - European Journal of …, 2021 - nature.com
Reproductive genetic carrier screening aims to offer couples information about their chance
of having children with certain autosomal recessive and X-linked genetic conditions. We …

[HTML][HTML] Known unknowns: building an ethics of uncertainty into genomic medicine

AJ Newson, SJ Leonard, A Hall, CL Gaff - BMC medical genomics, 2016 - Springer
Background Genomic testing has reached the point where, technically at least, it can be
cheaper to undertake panel-, exome-or whole genome testing than it is to sequence a single …

[PDF][PDF] Australian genomics: a federated model for integrating genomics into healthcare

Z Stark, T Boughtwood, P Phillips… - The American Journal of …, 2019 - cell.com
Australian Genomics is a national collaborative research partnership of more than 80
organizations piloting a whole-of-system approach to integrating genomics into healthcare …

[PDF][PDF] Australian Genomics: Outcomes of a 5-year national program to accelerate the integration of genomics in healthcare

Z Stark, T Boughtwood, M Haas, J Braithwaite… - The American Journal of …, 2023 - cell.com
Australian Genomics is a national collaborative partnership of more than 100 organizations
piloting a whole-of-system approach to integrating genomics into healthcare, based on …

[HTML][HTML] Impact of personal genomic risk information on melanoma prevention behaviors and psychological outcomes: a randomized controlled trial

AK Smit, M Allen, B Beswick, P Butow, H Dawkins… - Genetics in …, 2021 - Elsevier
Purpose We evaluated the impact of personal melanoma genomic risk information on sun-
related behaviors and psychological outcomes. Methods In this parallel group, open …

For your interest? The ethical acceptability of using non‐invasive prenatal testing to test 'purely for information'

Z Deans, AJ Clarke, AJ Newson - Bioethics, 2015 - Wiley Online Library
Non‐invasive prenatal testing (NIPT) is an emerging form of prenatal genetic testing that
provides information about the genetic constitution of a foetus without the risk of pregnancy …