Ethics of placebo-controlled trials of zidovudine to prevent the perinatal transmission of HIV in the Third World

N Engl J Med. 1998 Mar 19;338(12):836; author reply 840-1. doi: 10.1056/NEJM199803193381213.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Anti-HIV Agents / therapeutic use*
  • Clinical Trials as Topic / methods*
  • Control Groups
  • Developing Countries*
  • Ethical Relativism*
  • Ethics Committees, Research
  • Ethics, Medical*
  • Federal Government
  • Female
  • HIV Infections / prevention & control*
  • HIV Infections / transmission
  • Humans
  • Infectious Disease Transmission, Vertical / prevention & control*
  • Internationality
  • Placebos
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy
  • Pregnant Women*
  • Risk Assessment
  • Therapeutic Human Experimentation
  • Zidovudine / therapeutic use

Substances

  • Anti-HIV Agents
  • Placebos
  • Zidovudine