EditorialOpportunistic salpingectomy for women at low risk for development of ovarian carcinoma: The time has come
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Conflict of interest statement
The authors declare that there are no conflicts of interest.
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Cited by (20)
Cost-effectiveness of opportunistic salpingectomy for ovarian cancer prevention
2017, Gynecologic OncologyCitation Excerpt :The risk-reducing benefit likely extends beyond the already known risk reduction from tubal ligation [7–11]. This evidence has led gynecologists to perform opportunistic salpingectomies at the time of hysterectomy or tubal surgery for permanent contraception, and many major gynecologic societies in the United States and Canada support this practice change [12,13]. A recent study evaluating hysterectomy practices in a large health system revealed a significant increase in rates of hysterectomies being performed with salpingectomy (14.7% in 2011 to 72.7% in 2014, p < 0.001) [14].
PAX8 expression in ovarian surface epithelial cells
2015, Human PathologyCitation Excerpt :More recent evidence indicates that HGSOCs can originate from epithelial cells lining the fallopian tube fimbriae, through a precursor lesion termed serous tubal intraepithelial carcinoma (STIC). STICs are associated with 20% to 60% of sporadic HGSOCs [5–8], raising the possibility that the remaining 40% to 80% of HGSOCs may arise from an alternative cell of origin. Several studies have shown that paired box 8 (PAX8) is highly expressed in most HGSOCs [9–14], suggesting that overexpression of this transcription factor plays a critical role in this tumor type.
Identifying post-menopausal women at elevated risk for epithelial ovarian cancer
2015, Gynecologic OncologyCitation Excerpt :The addition of BSOR to hysterectomy in women who do not carry BRCA1/2 mutations was recently reported to show no negative effects on ovarian function or perioperative complications [8,11]. Efficacy of this approach remains to be demonstrated [12]. Post-menopausal women having hysterectomy for benign conditions must choose among prophylactic BSO, prophylactic BSOR, or retention of both ovaries and fallopian tubes.
Mevrouw, there is more regret and failure following a sterilization together with a caesarean, and all those hormones in pregnancy preclude rational judgement
2014, European Journal of Obstetrics and Gynecology and Reproductive BiologyThe postreproductive salpingectomy
2014, Fertility and SterilityHysterectomy with opportunistic salpingectomy versus hysterectomy alone
2019, Cochrane Database of Systematic Reviews