Making sense of randomization; responses of parents of critically ill babies to random allocation of treatment in a clinical trial
References (77)
- et al.
The therapeutic misconception: informed consent in psychiatric research
International Journal of Law and Psychiatry
(1982) Recruitment for an efficacy study in chemoprevention: the concerned smoker study
Preventive Medicine
(1989)- et al.
Informed consent in psychiatric research: preliminary findings from an ongoing investigation
Social Science & Medicine
(1985) - et al.
Patient perception of a long-term clinical trial: experience using a close-out questionnaire in the Studies of Left Ventricular Dysfunction (SOLVD) Trial
Controlled Clinical Trials
(1994) - et al.
How informed is informed consent? The BHAT experience
Controlled Clinical Trials
(1981) Shared understandings for informed consent: the relevance of psychological research on the provision of information
Social Science & Medicine
(1996)- et al.
Is informed consent in neonatal randomised clinical trials ritual?
Lancet
(1996) - et al.
Patients' willingness to enter clinical trials: measuring the association with perceived benefit and preference for decision participation
Social Science & Medicine
(1991) Participation in a clinical trial: the patients' point of view
Controlled Clinical Trials
(1985)- et al.
Redressing the balance: the ethics of not entering an eligible patient on a randomized clinical trial
Annals of Oncology
(1992)
Participation in medical research: the consent process as viewed by children, adolescents, young adults and physicians
Pediatrics
(1992)
Is it any good? The evaluation of therapy by participants in a clinical trial
Social Science & Medicine
(1989)
Telephone-based nursing intervention improves the effeiveness of the informed consent process in cancer clinical trials
Journal of Clinical Oncology
(1996)
Women's Views of Breast Cancer Treatment and Research
Your baby is in a trial
Lancet
(1995)
False hopes and best data: consent to research and the therapeutic misconception
Hastings Cent Report
(1987)
Parental opinions about biomedical research in children in Tours, France
Developmental Pharmacology Therapy
(1993)
The ethics of experimentation with human subjects
Scientific American
(1976)
Extracorporeal circulation in neonatal respiratory failure: a prospective randomized controlled study
Pediatrics
(1985)
Oncologists' reluctance to accrue patients onto clinical trials: an Illinois Cancer Center study
Journal of Clinical Oncology
(1991)
Ethics and ECMO
Statistical Science
(1989)
Patients' attitudes to participation in clinical trials
British Journal of Clinical Pharmacology
(1993)
Prospective randomised trial of conventional treatment or transport for ECMO in infants with PPHN [abstract 1160]
Pediatric Research
(1992)
Improving vaccine coverage in teenages
Experiences from a vaccine protection trial in Norway
European Journal of Public Health
(1994)
The hardest decision
Midwives Chronicle
(1994)
Informed consent: ethical, legal and medical implications for doctors and patients who participate in randomized clinical trials
British Medical Journal
(1983)
Attitudes toward clinical trials among patients and the public
Journal of the American Medical Association
(1982)
Minimizing harm and maximising benefit during innovation in health care: controlled or uncontrolled experimentation
Birth
(1986)
Randomisation and patient choice
Lancet
(1994)
Offering patients entry into clinical trials: preliminary study of the views of prospective participants
Journal of Medical Ethics
(1996)
Evaluation of the National Cancer Institute's clinical trials booklet
Journal of the National Cancer Institute
(1993)
Randomised trials and informed consent in neonatal medicine
British Medical Journal
(1986)
Advising AIDS patients who participate in clinical trials
AIDS Patient Care
(1994)
A testing time: a doctor's thoughts on having his patients participate in double blind study of ticlopidine
Discover
(1990)
Informed consent—consent difficult in paediatric oncology
British Medical Journal
(1994)
The UK Collaborative ECMO Trial
Midwives Chronicle
(1994)
The ethics of randomized clinical trials: two perspectives
New England Journal of Medicine
(1979)
Human Subjects in Medical Experimentation: A Sociological Study of the Conduct and Regulation of Clinical Research
(1975)
Cited by (250)
Decision making in a clinical trial for a life-threatening illness: Therapeutic expectation, not misconception
2022, Social Science and MedicineTreatment preference and recruitment to pediatric RCTs: A systematic review
2019, Contemporary Clinical Trials CommunicationsAn observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment
2018, Journal of Clinical EpidemiologyCitation Excerpt :Thus, perhaps unwittingly, by invoking a “computer” as the decision-making tool, recruiters are distanced from the potentially discomforting discussion with patients where they must acknowledge that there is uncertainty as to the best form of treatment. However, a problem with creating an impression that some decision-making agency exists is that it leads some patients to believe they will receive the best form of treatment for them—a therapeutic misconception [5,27]. The problems associated with a therapeutic misconception include that patients end up with unrealistic optimism about the treatment they will receive being best fitted to their condition [28] as well as not being clearly informed about the justification for the trial.
Engaging Bioethics: An Introduction with Case Studies: Second Edition
2023, Engaging Bioethics: An Introduction with Case Studies: Second Edition
Copyright © 1997 Published by Elsevier Ltd.