Scientific article
Standard gamble, time trade-off and rating scale: Experimental results on the ranking properties of QALYs

https://doi.org/10.1016/S0167-6296(96)00509-7Get rights and content

Abstract

This paper compares the relative performance of quality adjusted life years (QALYs) based on quality weights elicited by rating scale (RS), time trade-off (TTO) and standard gamble (SG). The standard against which relative performance is assessed is individual preference elicited by direct ranking. The correlation between predicted and direct ranking is significantly higher for TTO-QALYs than for RS-QALYs and SG-QALYs. This holds both based on mean Spearman rank correlation coefficients calculated per individual and based on two social choice rules: the method of majority voting and the Borda rule. Undiscounted TTO-QALYs are more consistent with direct ranking than discounted TTO-QALYs.

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      A recent Korean study24 found large differences in the utility scores between SG/TTO and VAS and much narrower differences between SG and TTO. In our research we find no substantive difference between SG and TTO scores, which contrasts with much of the literature and is plausibly because of our use of the TTO variant that excludes health states worse than death.12,24,25 It is, however, also likely that the homogenous and highly educated nature of our sample served to diminish the difference between SG and TTO and that, among the general population less familiar with risk concepts, a gap would emerge more in line with other studies.

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