Liver TransplantationComplications and treatments of donors and recipients in living-related liver transplantation
Section snippets
Subjects
From July 1991 to November 1997, 25 patients underwent a living-related liver transplantation in the Second Department of Surgery, Tohoku University, School of Medicine. There were 20 cases of biliary atresia, 2 of primary biliary cirrhosis, and 1 each of Byler’s disease, patent ductus venosus, and primary sclerosing cholangitis. Ages of recipients at the time of transplantation ranged from 5 months to 48 years. The donors for the living-related liver transplantation were healthy parents, sons,
Mortality
The 1-year survival rate was about 75%. The causes of death were pulmonary hypertension in two patients, arterial thrombosis in one, arterial and portal vein thrombosis in one, necrotizing fascitis in one, outflow block in one, and hepatic failure after severe rejection in one. In all cases, the hepatic artery was anastomosed under microscopic surgery. We encountered two cases of hepatic arterial thrombosis. All donors are now alive without any liver dysfunction.
Complications and treatments in donors
Mean time of donor
Discussion
Living-related liver transplantation is done in Eastern and European countries because of the donor shortage. Since 1989, more than 500 patients in Japan have received a living-related liver transplantation in more than 20 institutes. The procedures of the donor and recipient operations are almost established, but several problems still remain. Exquisite technique is required for the donor operation. In our institute, 19 donors had no complications and their liver function, ie, serum
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Cited by (30)
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