Table 2

Agreement with payment statements

Mean level of agreement
Mean (SD)
% respondents who indicated a level of agreement greater than 4 – ‘somewhat agree’ConceptStatement describing payment attitude
Public
n=264
CHIM experts
n=36
T-test, p valuePublic
n=264
CHIM experts
n=36
5.30 (1.07)2.47 (2.02)t(37.72)=8.24,
p<0.001
91.727.8Risk payment and harm compensationRisk should be accounted for in the payment and extra compensatory payment should be given for actual harm.
2.25 (1.95)2.88 (2.24)t(41.09)=−1.59,
p=0.12
2545.7No risk payment but harm compensationRisk should not be accounted for in the payment but extra compensatory payment should be given for actual harm.
3.65 (1.67)NANA57.2NAPayment as coercionOffering large amounts of money to become a Challenge Study participant could force people to participate in this research.
4.21 (1.41)NANA71.6NAPayment as an undue inducementOffering large amounts of money to participants for being involved in Challenge Studies could impair participants’ judgement. This means they may choose to become involved in the research despite it not being in their best interests.
  • Respondents were asked to indicate their level of agreement with each statement on a slider scale from 0: strongly disagree to 6: strongly agree. The mean level of agreement for each statement was compared between CHIM experts and public respondents by using t-tests. As the CHIM experts survey did not include all statements, ‘NA’ indicates the questions that were not in the experts’ survey.

  • CHIM, Controlled Human Infection Model.