Payment factors
| Payment factor | Mean rank of importance Mean (SD) | % of participants who thought factor should not be accounted for in payment | |||
| Public n=264 | CHIM experts n=33 | T-test, p value | Public n=264 | CHIM experts n=35 | |
| Risk of serious side effects and death involved in the study | 1.24 (0.80) | 3.85 (2.45) | t(32.86)=−6.08, p<0.001 | 1.1 | 37.1 |
| Pain involved in the study | 2.48 (0.86) | 4.00 (1.20) | t(36.25)=−7.06, p<0.001 | 0.8 | 8.6 |
| Number of invasive investigations involved in the study (eg, blood tests and investigations requiring sedation) | 3.18 (1.01) | 2.67 (1.02) | t(40.32)=2.73, p=0.009 | 0.4 | 2.9 |
| Time required in the study | 4.29 (1.43) | 2.48 (1.75) | t(37.61)=5.69, p<0.001 | 1.5 | 0 |
| Number of non-invasive investigations involved in the study (eg, urine sample, saliva swab and ultrasound) | 4.95 (1.00) | 4.58 (1.25) | t(37.30)=1.67, p>0.05 | 7.6 | 8.6 |
| Inconvenience involved in the study | 4.97 (1.12) | 3.55 (1.50) | t(36.62)=5.28, p<0.001 | 10.6 | 0 |
Public and expert respondents were asked to rank the list of payment factors in order of importance when determining payment for CHIM participants. They were also asked if any payment factor should not be accounted for in payment. The mean rank of importance for each payment factor was compared between CHIM experts and public respondents using t-tests.
CHIM, Controlled Human Infection Model.