Table 1

Participants’ knowledge about placebos

ItemCorrect answerTotal % correct (n)Read/heard about placebos (n=143)† % correct (n)Not read/heard about placebos (n=64)† % correct (n)
A pill with aspirin in it is called a ‘placebo’ pillFalse98.1% (206)98.6% (141)96.9% (62)
The placebo effect can work because of people’s expectationsTrue95.2% (200)99.3% (142)85.9% (55)**
Placebo treatments are only effective for people who are not very intelligentFalse96.7% (203)97.9% (140)93.8% (60)
Placebo treatments can help to treat pain conditionsTrue79.5% (167)82.5% (118)71.9% (46)
Placebo treatments do not help to relieve any medical symptomsFalse72.9% (153)76.2% (109)65.6% (42)
Placebo pain treatments only relieve imaginary pain (ie, pain that was not real in the first place)False85.2% (179)89.5% (128)75.0% (48)**
A pill with no medicine in it is called a ‘placebo’ pillTrue91.9% (193)97.9% (140)78.1% (50)**
The placebo effect can work because of conditioningTrue74.3% (156)74.8% (107)73.4% (47)
Real changes in the brain can occur when you receive a placebo (such as the release of chemicals called opioids)True83.8% (176)88.1% (126)73.4% (47)*
Placebo effects are imaginary and have no real physical effects on our bodyFalse81.0% (170)83.2% (119)76.6% (49)
Placebo effects only occur in experiments and research trialsFalse86.2% (181)90.2% (129)76.6% (49)**
A placebo pill can have side effectsTrue31.9% (67)34.3% (49)28.1% (18)
The placebo effect can help us to get better during normal medical treatmentsTrue79.5% (167)83.9% (120)68.8% (44)*
The colour of a placebo pill can change how effective it isTrue55.2% (116)60.1% (86)43.8% (28)*
Placebo treatments are only effective for people who lie about their symptomsFalse96.7% (203)99.3% (142)90.6% (58)**
  • *p<0.05, **p<0.01, significant χ2.

  • †Three participants did not specify whether they had previously read or heard about placebos.