Developed country studies | Developing country studies | ||||
Author | Country | Understood risks or side effects | Author | Country | Understood risks or side effects |
Daugherty et al, 200050 | USA | 100% named >1 side effect | Pace et al, 200528 | Thailand | 98% recognised side effects |
Harrison et al, 199555 | USA | 89% recognised side effects | Pitisuttithum et al, 199735 | Thailand | 97% recognised side effects |
Knifed et al, 200838 | Canada | 71% knew at least one general risk† | Minnies et al, 200824 | South Africa | 79.2% knew risks |
Benson et al, 198560 | USA | Depression study: 62% knew risks | Leach et al, 199933 | The Gambia | 53% named ≥1 side effect |
Schizophrenia study: 42% knew risks | |||||
Howard et al, 198163 | USA | 61% could name 1 side effect | Oduro et al, 200822 | Ghana | 20% knew direct risks |
Miller et al, 199458 | USA | 48% named and 86% recognised >1 risk | Pace et al, 200529 | Uganda | 18% named 1 or more side effects |
Ravina et al, 201036 | USA | 47% knew which drugs had highest risks, 93% knew PD could get better, worse or not change | Krosin et al, 200626 | Mali | 7% said there were side effects‡ |
Estey et al, 199457 | Canada | 41% named >1 risk | Kaewpoonsri et al, 200625 | Thailand | 6.6% recalled being told of risks |
Van Stuijvenberg et al, 199853 | The Netherlands | 40% knew side effects | |||
Joffe et al, 200149 | USA | 37% knew research risks | |||
Penman et al, 198461 | USA | 31% named >3 of 11 risks | |||
Criscione et al, 200344 | USA | 30% knew there were risks§ | |||
Bergler et al, 198064 | USA | 28% (at start), 3% (3 months later) | |||
Bergenmar et al, 200837 | Sweden | 18% knew research risks | |||
Schats et al, 200347 | The Netherlands | 6% knew side effects |
↵* Arranged from highest to lowest.
↵† 29% did not recall ANY risks of the trial drug, the rest of the participants could name general risks, and at most participants could name up to four specific risks or side effects.
↵‡ The question was complex and multi-choice. The correct answer was the only one that included a mention of side effects. However, it also included information about the potential benefits of the medicine (eg, that it could prevent malaria and correct other health problems).
↵§ But were not asked to name or identify them.
PD, Parkinson's disease.