Summary for categorical variables | Consent Number (%) | Assent Number (%) | Total | Odds of consent of baseline (95% CI) | p Value | |
Diagnosis | Vascular dementia | 12 (42.9%) | 16 (57.1%) | 28 | Baseline | 0.015 |
Alzheimer’s disease | 30 (20.4%) | 117 (79.6%) | 147 | 0.342 (0.146, 0.799) | ||
Gender | Male | 22 (31.4%) | 48 (68.6%) | 70 | Baseline | 0.062 |
Female | 20 (19.0%) | 85 (21%) | 105 | 0.513 (0.255, 1.035) | ||
MMSE score | 12–23 | 13 (11.6%) | 99 (88.4%) | 112 | Baseline | <0.001 |
24–26 | 28 (45.2%) | 34 (54.8%) | 62 | 6.271 (2.920, 13.471) | ||
Maximum | 26 | 26 | ||||
Minimum | 19 | 12 | ||||
Summary for continuous variables | Consent | Assent | Total | Odds ratio (95% CI) | p Value | |
Age (years) | Mean (SD) | 75.9 (7.0) | 80.7 (7.3) | 79.5 (7.6) | 0.916 (0.872, 0.962) | <0.001 |
Minimum | 57 | 57 | 57 | |||
Maximum | 89 | 96 | 96 | |||
Education (years) | Mean (SD) | 11.5 (3.4) | 10.6 (2.5) | 10.8 (2.7) | 1.116 (0.991, 1.257) | 0.074 |
Minimum | 6 | 7 | 6 | |||
Maximum | 22 | 23 | 23 | |||
Duration of dementia (months) | Median | 30.0 | 42.0 | 36.0 | 0.990 (0.977, 1.002) | 0.077 |
Minimum | 6 | 4 | 4 | |||
Lower quartile | 17.5 | 24.0 | 24.0 | |||
Upper quartile | 48.0 | 60.0 | 60.0 | |||
Maximum | 156 | 216 | 216 | |||
ADAS-COG (score)* | Median | 15.0) | 24.0 | 21.0 | 0.830 (0.771,0.893) | <0.001 |
Minimum | 6.0 | 8.0 | 6.0 | |||
Lower quartile | 11.7 | 17.5 | 15.0 | |||
Upper quartile | 17.0 | 32.5 | 29.0 | |||
Maximum | 35.0 | 56.0 | 56.0 |
Normally distributed data (mean and sd) and non-normal data (median and interquartile range) showing results of single variable comparisons of binary variables associated with presence/absence of capacity to consent to research. *Only ADAS-Cog score and age found to be independently associated with capacity using all the above variables in a multivariable logistic regression.