Table 2

Medium-quality evidence on the prevalence of depression in different categories of patientsc

	Prevalence of depression in euthanasia/PAS requests	Prevalence of depression in granted euthanasia/PAS requests	Prevalence of depression in population not requesting euthanasia/PAS
The Netherlands		25% of all patients had depression to great/very great extent, 29% to a lesser extent23
		5% of all patients had depression as a motivating factor (4/87)24
		12% of ALS patients used antidepressants in end-stage, 11% had symptoms of depression in end-stage, 23% had anhedonia, 21% depressed mood, 13% feelings of guilt25	11% of ALS patients used antidepressants in end-stage, 16% had symptoms of depression in end-stage, 24% had anhedonia, 18% depressed mood, 9% feelings of guilt25
Non-legal: Washington state, USA	55% of all patients had severe depression or depressed mood (114/207)26
Non-legal: Toronto, Canada	50% of HIV patients had a diagnosis of depression (10/20)27		17% of HIV patients had a diagnosis of depression (2/12)27