Table 1

 Chronology of controversy surrounding ARDSNet ventilator trial

ARDSNet; Acute Respiratory Distress Syndrome Network; OHRP, (US) Office for Human Research Protections.
March 1996 through March 1999Conduct of trial
May 2000Trial report published
July 2002OHRP relays concerns of complainants to ARDSNet. An ongoing ARDSNet trial is suspended
December 2002Article by critics published
December 2002 through September 2003Debate about trial published in the Correspondence Section of the American Journal of Respiratory and Critical Care Medicine
July 2003After review of the opposing contentions and consultation with independent experts, OHRP permits resumption of suspended trial contingent upon further review by institutional review boards