RT Journal Article SR Electronic T1 Public involvement in the governance of population-level biomedical research: unresolved questions and future directions JF Journal of Medical Ethics JO J Med Ethics FD BMJ Publishing Group Ltd and Institute of Medical Ethics SP 522 OP 525 DO 10.1136/medethics-2020-106530 VO 47 IS 7 A1 Sonja Erikainen A1 Phoebe Friesen A1 Leah Rand A1 Karin Jongsma A1 Michael Dunn A1 Annie Sorbie A1 Matthew McCoy A1 Jessica Bell A1 Michael Burgess A1 Haidan Chen A1 Vicky Chico A1 Sarah Cunningham-Burley A1 Julie Darbyshire A1 Rebecca Dawson A1 Andrew Evans A1 Nick Fahy A1 Teresa Finlay A1 Lucy Frith A1 Aaron Goldenberg A1 Lisa Hinton A1 Nils Hoppe A1 Nigel Hughes A1 Barbara Koenig A1 Sapfo Lignou A1 Michelle McGowan A1 Michael Parker A1 Barbara Prainsack A1 Mahsa Shabani A1 Ciara Staunton A1 Rachel Thompson A1 Kinga Varnai A1 Effy Vayena A1 Oli Williams A1 Max Williamson A1 Sarah Chan A1 Mark Sheehan YR 2021 UL http://jme.bmj.com/content/47/7/522.abstract AB Population-level biomedical research offers new opportunities to improve population health, but also raises new challenges to traditional systems of research governance and ethical oversight. Partly in response to these challenges, various models of public involvement in research are being introduced. Yet, the ways in which public involvement should meet governance challenges are not well understood. We conducted a qualitative study with 36 experts and stakeholders using the World Café method to identify key governance challenges and explore how public involvement can meet these challenges. This brief report discusses four cross-cutting themes from the study: the need to move beyond individual consent; issues in benefit and data sharing; the challenge of delineating and understanding publics; and the goal of clarifying justifications for public involvement. The report aims to provide a starting point for making sense of the relationship between public involvement and the governance of population-level biomedical research, showing connections, potential solutions and issues arising at their intersection. We suggest that, in population-level biomedical research, there is a pressing need for a shift away from conventional governance frameworks focused on the individual and towards a focus on collectives, as well as to foreground ethical issues around social justice and develop ways to address cultural diversity, value pluralism and competing stakeholder interests. There are many unresolved questions around how this shift could be realised, but these unresolved questions should form the basis for developing justificatory accounts and frameworks for suitable collective models of public involvement in population-level biomedical research governance.No data are available.