PT - JOURNAL ARTICLE AU - Anneke M Lucassen AU - John Henry McDermott AU - William Newman TI - Using a biomarker acutely to identify babies at risk of serious adverse effects from antibiotics: where is the ‘Terrible Moral and Medical Dilemma’? AID - 10.1136/medethics-2020-107048 DP - 2021 Feb 01 TA - Journal of Medical Ethics PG - 117--118 VI - 47 IP - 2 4099 - http://jme.bmj.com/content/47/2/117.short 4100 - http://jme.bmj.com/content/47/2/117.full SO - J Med Ethics2021 Feb 01; 47 AB - We thank Parker and Wright for engaging in this roundtable debate in such a spirited way. The ‘Pharmacogenetic [test] to Avoid Loss of Hearing’ (PALOH) Trial is the first time a genetic point of care test has been applied in the acute neonatal setting; therefore, it is not surprising that questions have been raised which require debate, discussion and clarification. Parker and Wright misattribute several assumptions to the roundtable authors, which we would like to clarify here. Since they raise wider questions about the PALOH trial itself, several of the roundtable discussants have made a joint response.