PT  - JOURNAL ARTICLE
AU  - Robert Steel
AU  - Lara Buchak
AU  - Nir Eyal
TI  - Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines
AID  - 10.1136/medethics-2020-106501
DP  - 2020 Dec 01
TA  - Journal of Medical Ethics
PG  - 808--812
VI  - 46
IP  - 12
4099  - http://jme.bmj.com/content/46/12/808.short
4100  - http://jme.bmj.com/content/46/12/808.full
SO  - J Med Ethics2020 Dec 01; 46
AB  - To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection (or ‘challenge’) trials. These trials would involve the deliberate exposure of relatively few young, healthy volunteers to SARS-CoV-2. We defend this proposal against the charge that there is still too much uncertainty surrounding the risks of COVID-19 to responsibly run such a trial.