TY - JOUR T1 - Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines JF - Journal of Medical Ethics JO - J Med Ethics SP - 808 LP - 812 DO - 10.1136/medethics-2020-106501 VL - 46 IS - 12 AU - Robert Steel AU - Lara Buchak AU - Nir Eyal Y1 - 2020/12/01 UR - http://jme.bmj.com/content/46/12/808.abstract N2 - To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection (or ‘challenge’) trials. These trials would involve the deliberate exposure of relatively few young, healthy volunteers to SARS-CoV-2. We defend this proposal against the charge that there is still too much uncertainty surrounding the risks of COVID-19 to responsibly run such a trial. ER -