PT - JOURNAL ARTICLE AU - Eric Vogelstein TI - Decision-making at the border of viability: determining the best interests of extremely preterm infants AID - 10.1136/medethics-2019-105816 DP - 2020 Nov 01 TA - Journal of Medical Ethics PG - 773--779 VI - 46 IP - 11 4099 - http://jme.bmj.com/content/46/11/773.short 4100 - http://jme.bmj.com/content/46/11/773.full SO - J Med Ethics2020 Nov 01; 46 AB - This paper proposes and employs a framework for determining whether life-saving treatment at birth is in the best interests of extremely preterm infants, given uncertainty about the outcome of such a choice. It argues that given relevant data and plausible assumptions about the well-being of babies with various outcomes, it is typically in the best interests of even the youngest preterm infants—those born at 22 weeks gestational age—to receive life-saving treatment at birth.