RT Journal Article
SR Electronic
T1 Uterus transplantation in women who are genetically XY
JF Journal of Medical Ethics
JO J Med Ethics
FD BMJ Publishing Group Ltd and Institute of Medical Ethics
SP 687
OP 689
DO 10.1136/medethics-2018-105222
VO 45
IS 10
A1 Amani Sampson
A1 Laura L. Kimberly
A1 Kara N. Goldman
A1 David L. Keefe
A1 Gwendolyn P. Quinn
YR 2019
UL http://jme.bmj.com/content/45/10/687.abstract
AB Uterus transplantation is an emerging technology adding to the arsenal of treatments for infertility; specifically the only available treatment for uterine factor infertility. Ethical investigations concerning risks to uteri donors and transplant recipients have been discussed in the literature. However, missing from the discourse is the potential of uterus transplantation in other groups of genetically XY women who experience uterine factor infertility. There have been philosophical inquiries concerning uterus transplantation in genetically XY women, which includes transgender women and women with complete androgen insufficiency syndrome. We discuss the potential medical steps necessary and associated risks for uterus transplantation in genetically XY women. Presently, the medical technology does not exist to make uterus transplantation a safe and effective option for genetically XY women, however this group should not be summarily excluded from participation in trials. Laboratory research is needed to better understand and reduce medical risk and widen the field to all women who face uterine factor infertility.