TY - JOUR T1 - Uterus transplantation in women who are genetically XY JF - Journal of Medical Ethics JO - J Med Ethics SP - 687 LP - 689 DO - 10.1136/medethics-2018-105222 VL - 45 IS - 10 AU - Amani Sampson AU - Laura L. Kimberly AU - Kara N. Goldman AU - David L. Keefe AU - Gwendolyn P. Quinn Y1 - 2019/10/01 UR - http://jme.bmj.com/content/45/10/687.abstract N2 - Uterus transplantation is an emerging technology adding to the arsenal of treatments for infertility; specifically the only available treatment for uterine factor infertility. Ethical investigations concerning risks to uteri donors and transplant recipients have been discussed in the literature. However, missing from the discourse is the potential of uterus transplantation in other groups of genetically XY women who experience uterine factor infertility. There have been philosophical inquiries concerning uterus transplantation in genetically XY women, which includes transgender women and women with complete androgen insufficiency syndrome. We discuss the potential medical steps necessary and associated risks for uterus transplantation in genetically XY women. Presently, the medical technology does not exist to make uterus transplantation a safe and effective option for genetically XY women, however this group should not be summarily excluded from participation in trials. Laboratory research is needed to better understand and reduce medical risk and widen the field to all women who face uterine factor infertility. ER -