TY - JOUR T1 - Moral reasons to edit the human genome: picking up from the Nuffield report JF - Journal of Medical Ethics JO - J Med Ethics SP - 514 LP - 523 DO - 10.1136/medethics-2018-105084 VL - 45 IS - 8 AU - Christopher Gyngell AU - Hilary Bowman-Smart AU - Julian Savulescu Y1 - 2019/08/01 UR - http://jme.bmj.com/content/45/8/514.abstract N2 - In July 2018, the Nuffield Council of Bioethics released its long-awaited report on heritable genome editing (HGE). The Nuffield report was notable for finding that HGE could be morally permissible, even in cases of human enhancement. In this paper, we summarise the findings of the Nuffield Council report, critically examine the guiding principles they endorse and suggest ways in which the guiding principles could be strengthened. While we support the approach taken by the Nuffield Council, we argue that detailed consideration of the moral implications of genome editing yields much stronger conclusions than they draw. Rather than being merely ‘morally permissible’, many instances of genome editing will be moral imperatives. ER -