RT Journal Article SR Electronic T1 Treatment-resistant depression and physician-assisted death JF Journal of Medical Ethics JO J Med Ethics FD BMJ Publishing Group Ltd and Institute of Medical Ethics SP 885 OP 886 DO 10.1136/medethics-2015-103060 VO 41 IS 11 A1 Franklin G MIller YR 2015 UL http://jme.bmj.com/content/41/11/885.abstract AB In a recent article, Udo Schuklenk and Suzanne van de Vathorst argued in favour of a legal option of physician-assisted death for patients with ‘treatment-resistant’ depression. In this commentary, I contend that their argument neglects the important consideration of the professional integrity of physicians. In light of this consideration, coupled with uncertainty about whether additional interventions with the patient can improve quality of life and restore the will to live, it is not appropriate to include patients with ‘treatment-resistant’ depression within a legal option of physician-assisted death.