TY - JOUR T1 - Ethical and economic considerations of rare diseases in ethnic minorities: the case of mucopolysaccharidosis VI in Colombia JF - Journal of Medical Ethics JO - J Med Ethics SP - 699 LP - 700 DO - 10.1136/medethics-2011-100204 VL - 38 IS - 11 AU - Diego Rosselli AU - Juan-David Rueda AU - Martha Solano Y1 - 2012/11/01 UR - http://jme.bmj.com/content/38/11/699.abstract N2 - Mucopolysaccharidosis VI is an autosomal recessive lysosomal storage disorder associated with severe disability and premature death. The presence of a mucopolysaccharidosis-like disease in indigenous ethnic groups in Colombia can be inferred from archaeological findings. There are several indigenous patients with mucopolysaccharidosis VI currently receiving enzyme replacement therapy. We discuss the ethical and economic considerations, regarding both direct and indirect costs, of a high-cost orphan disease in a marginalised minority population in a developing country. ER -