TY - JOUR T1 - The cost of autonomy: estimates from recent advances in living donor kidney transplantation JF - Journal of Medical Ethics JO - J Med Ethics SP - 155 LP - 159 DO - 10.1136/jme.2009.034306 VL - 36 IS - 3 AU - Phedias Diamandis Y1 - 2010/03/01 UR - http://jme.bmj.com/content/36/3/155.abstract N2 - Autonomy, an individual's right to make personal decisions regarding his/her own health, represents one of the major ethical principles of medicine. While there are many examples citing the benefits this right provides for the individual, the impact that personal healthcare decisions have on others is often neglected. Here, evidence from end-stage renal disease is reviewed to hypothesise the creation of a universal kidney donation programme that although provides unparalleled benefits to its citizens, relies on the participation of a large proportion of the society. Given that this essay also addresses the public's major concerns regarding kidney donation, one of the only remaining implementation barriers is the individuals' right not to participate. Therefore, irrespective of the humane and complex emotionally laden reasons for not enrolling in such programmes, this essay provides some estimates of the significant resource and quality of life costs associated with autonomy. Assuming humans are competent to make informed personal healthcare choices, similar to recent efforts to increase awareness about the negative impact of certain lifestyle choices on global warming, citizens should also be better informed about the medical costs their autonomy has on society. ER -