PT - JOURNAL ARTICLE AU - Gerber, Andreas AU - Hentzelt, Frieder AU - Lauterbach, Karl W TI - Can evidence-based medicine implicitly rely on current concepts of disease or does it have to develop its own definition? AID - 10.1136/jme.2006.017913 DP - 2007 Jul 01 TA - Journal of Medical Ethics PG - 394--399 VI - 33 IP - 7 4099 - http://jme.bmj.com/content/33/7/394.short 4100 - http://jme.bmj.com/content/33/7/394.full SO - J Med Ethics2007 Jul 01; 33 AB - Decisions in healthcare are made against the background of cultural and philosophical definitions of disease, sickness and illness. These concepts or definitions affect both health policy (macro level) and research (meso level), as well as individual encounters between patients and physicians (micro level). It is therefore necessary for evidence-based medicine to consider whether any of the definitions underlying research prior to the hierarchisation of knowledge are indeed compatible with its own epistemological principles.