TY - JOUR T1 - Genetically selected baby free of inherited predisposition to early-onset Alzheimer’s disease JF - Journal of Medical Ethics JO - J Med Ethics SP - 290 LP - 290 DO - 10.1136/jme.28.5.290 VL - 28 IS - 5 AU - M Spriggs Y1 - 2002/10/01 UR - http://jme.bmj.com/content/28/5/290.abstract N2 - Is it right to use pre-implantation genetic diagnosis to select an embryo free of the gene for early-onset Alzheimer’s disease? A 30 year old woman with the gene for early-onset Alzheimer’s disease, who seems certain to develop the disease by the time she is 40, has used IVF and preimplantation genetic diagnosis to select an embryo that is free of the mutant gene. The woman, a geneticist, has given birth to a mutation-free child. This marks the first time that preimplantation genetic diagnosis has been used to “weed out” an embryo with the defect.1–3Early-onset Alzheimer’s is an inherited, incurable disease striking people … ER -