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The ethics of synthetic DNA
  1. Adrian Villalba1,2,
  2. Anna Smajdor3,
  3. Iain Brassington4,
  4. Daniela Cutas5
  1. 1Université Paris Cité, Paris, France
  2. 2University of Granada, Granada, Spain
  3. 3IFIKK, University of Oslo, Oslo, Norway
  4. 4CSEP/ Dept of Law, University of Manchester, Manchester, UK
  5. 5Clinical Sciences, Lund University, Lund, Sweden
  1. Correspondence to Dr Adrian Villalba; adri.vife{at}gmail.com

Abstract

In this paper, we discuss the ethical concerns that may arise from the synthesis of human DNA. To date, only small stretches of DNA have been constructed, but the prospect of generating human genomes is becoming feasible. At the same time, the significance of genes for identity, health and reproduction is coming under increased scrutiny. We examine the implications of DNA synthesis and its impact on debates over the relationship with our DNA and the ownership of our genes, its potential to disrupt common understandings of reproduction and privacy, and the way in which synthetic DNA challenges traditional associations between genes and identity. We explore the degree to which synthetic DNA may further undermine overgeneticised accounts of identity, health, reproduction, parenthood and privacy that are prevalent in the public domain and in some areas of policy-making. While avoiding making normative claims of our own, we conclude that there is a need for reflection on the ethical implications of these developing technologies before they are on us.

  • Ethics
  • In Vitro Techniques
  • Reproductive Medicine

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Footnotes

  • X @villalbaciencia, @acsmajdor, @ibrasso

  • Contributors AV and AS wrote the first draft. IB and DC expanded it. All authors contributed substantially to all parts of the paper, approved the final submission, and take responsibility for the content.

  • Funding Work towards this publication has benefitted from funding from the Víctor Grífols i Lucas Foundation (BEC-2024-007) and the Marcus and Amalia Wallenberg Foundation (MAW2020.0074).

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.