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Funding DW was supported for this work by a grant from the Wellcome trust 203132/Z/16/Z and by the UKRI/ AHRC funded UK Ethics Accelerator project, grant number AH/V013947/1.
Disclaimer The funders had no role in the preparation of this manuscript or the decision to submit for publication.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Commissioned; internally peer reviewed.
Data availability statement There are no data associated with this paper.
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