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I am happy that my paper provoked a response from the Health Research Authority (HRA) and that they have taken the opportunity to clarify this area—I want to respond in part to some of their comments, while accepting that some are accurate.1 ,2
While I am gladdened that generic advertising must now be submitted for review for stage 1 clinical trials since 2013 (there was some crossover between the original conception of the paper and this time period), I have to say this is at best only partially reassuring.
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