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From genomic databases to translation: a call to action
  1. Bartha Maria Knoppers1,
  2. Jennifer R Harris2,
  3. Paul R Burton3,
  4. Madeleine Murtagh3,
  5. David Cox4,
  6. Mylène Deschênes5,
  7. Isabel Fortier5,
  8. Thomas J Hudson6,
  9. Jane Kaye7,
  10. Klaus Lindpaintner8
  1. 1Department of Human Genetics, McGill University, Montreal, Quebec, Canada
  2. 2Norwegian Institute of Public Health, Oslo, Norway
  3. 3Department of Health Sciences, University of Leicester, Leicester, UK
  4. 4Biotherapeutics and Innovation Center, Pfizer Inc., Cambridge, Massachusetts, USA
  5. 5Public Population Project in Genomics (P3G), Montreal, Quebec, Canada
  6. 6Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada
  7. 7Department of Public Health, University of Oxford, Oxford, UK
  8. 8Strategic Diagnostics Inc. (SDI), Newark, New Jersey, USA
  1. Correspondence to Professor Bartha Maria Knoppers, McGill University, Director, Centre of Genomics and Policy, 740 Dr Penfield Avenue, McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, H3A 1A4, Canada; bartha.knoppers{at}


The rapid rise of international collaborative science has enabled access to genomic data. In this article, it is argued that to move beyond mapping genomic variation to understanding its role in complex disease aetiology and treatment will require extending data sharing for the purposes of clinical research translation and implementation.

  • Data Sharing
  • genomic databases
  • Translational research

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  • Competing interests None.

  • Provenance and peer review Not commissioned; not externally peer reviewed.

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