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Collection, storage and use of blood samples for future research: views of Egyptian patients expressed in a cross-sectional survey
  1. Alaa Abou-Zeid1,
  2. Henry Silverman2,
  3. Magdi Shehata3,
  4. Mohamed Shams4,
  5. Mervat Elshabrawy5,
  6. Tamer Hifnawy6,
  7. Safa Abdel Rahman7,
  8. Bahiga Galal8,
  9. Hany Sleem9,
  10. Nabiel Mikhail10,
  11. Nadia Moharram11
  1. 1Faculty of Medicine, Cairo University, Cairo, Egypt
  2. 2University of Maryland School of Medicine, Baltimore, Maryland, USA
  3. 3Faculty of Science, Ain Shams University, Cairo, Egypt
  4. 4National Cancer Institute, Cairo University, Cairo, Egypt
  5. 5Faculty of Medicine, Suez Canal University, Ismalia, Egypt
  6. 6Faculty of Medicine, Beni Suef University, Beni Suif, Egypt
  7. 7Faculty of Nursing, Menia University, Menia, Egypt
  8. 8Faculty of Nursing, Menofeya University, Menofeya, Egypt
  9. 9National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt
  10. 10South Egypt Cancer Institute, Assuit University, Assuit, Egypt
  11. 11Central Public Health Laboratories, Cairo, Egypt
  1. Correspondence to Dr Alaa Abou-Zeid, Department of Community Medicine, Cairo University, Cairo, Egypt; alaabouzeid{at}


Objective To determine the attitudes of Egyptian patients regarding their participation in research and with the collection, storage and future use of blood samples for research purposes.

Design Cross-sectional survey.

Study population Adult Egyptian patients (n=600) at rural and urban hospitals and clinics.

Results Less than half of the study population (44.3%) felt that informed consent forms should provide research participants the option to have their blood samples stored for future research. Of these participants, 39.9% thought that consent forms should include the option that future research be restricted to the illness being studied. A slight majority (66.2%) would donate their samples for future genetic research. Respondents were more favourable towards having their blood samples exported to other Arab countries (62.0%) compared with countries in Europe (41.8%, p<0.001) and to the USA (37.2%, p<0.001).

Conclusions This study shows that many individuals do not favour the donation of a blood sample for future research. Of those who do approve of such future research, many favour a consent model that includes an option restricting the future research to the illness being studied. Also, many Egyptians were hesitant to have their blood samples donated for genetic research or exported out of the Arab region to the USA and European countries. Further qualitative research should be performed to determine the underlying reasons for many of our results.

  • History of health ethics/bioethics
  • informed consent

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  • Funding Supported by Fogarty International Center, National Institutes of Health, USA, grant 25TW007090.

  • Competing interests None.

  • Ethics approval The study obtained ethics approval from the research ethics committees at National Cancer Institute, Cairo University, the National Hepatology and Tropical Medicine Research Institute, and the University of Maryland School of Medicine, Baltimore, Maryland, USA.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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