Deep-brain stimulation has been used to treat advanced Parkinson disease and other neurological and psychiatric disorders that have not responded to other treatments. While deep-brain stimulation can modulate overactive or underactive regions of the brain and thereby improve motor function, it can also cause changes in a patient’s thought and personality. This paper discusses the trade-offs between the physiological benefit of this technique and the potential psychological harm.
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Funding: The writing of the paper was supported in part by the Canadian Institutes of Health Research, NNF 80045, States of Mind: Emerging Issues in Neuroethics.
Competing interests: None.
Provenance and peer review: Not commissioned; not externally peer reviewed.